| |
MM-4 |
MM-6 |
MM-12 |
MM-192 |
MM-384 |
ABI 3900 |
ABI 3400 |
ABI Expedite 8909 w/MOSS (discontinued) |
Gene Machines Polyplex |
| Number of oligos synthesized without user intervention |
4 |
6 |
12 |
192 |
384 |
48 |
4 |
16 |
96 |
| Number of oligos Synthesized Simultaneously |
4 |
6 |
12 |
192 |
384 |
48 |
4 |
2 |
96 |
| Number of 20-mers produced in a given time |
4 in 2.5 hours |
6 in 2 hours |
12 in 2.5 hours |
384 in 10 hours |
384 in 6 hours |
288 in 10 hours |
4-25mers in 4 hours (cleavage included) |
2 in 2.5hours |
96 in 3 hours |
| Scale Range |
50-5000nmole |
50-50000nmole |
50-50000nmole |
5-5000nmole |
5-5000nmole |
40-1000nmole |
40-1000nmole |
40-15000nmole |
up to 1000nmole |
| Number of Amidite ports |
10 |
10+ |
10+ |
10+ |
10+ |
7 for each bank of 24 |
8 |
9 |
8 |
| 96 well format |
|
|
|
X |
X |
|
|
|
X |
| Trityl Collect/monitor |
X |
X |
X |
|
|
|
X |
X |
X |
| Columns or plate synthesis |
|
|
|
X |
X |
|
|
|
X |
| Efficient reagent use |
X |
X |
X |
X |
X |
X |
X |
X |
continues to add Ancillary reagents after oligo is completed if different lengths are being synthesized |
| Dedicated Thio Bottle |
X |
X |
X |
X |
X |
|
X |
X |
|
| Computer and software included and pre configured |
X |
X |
X |
X |
X |
X |
|
|
? |
| Short cycle times |
X |
X |
X |
X |
X |
X |
X |
X |
X |
| World Wide service |
X |
X |
X |
X |
X |
X |
X |
X |
X |
| Standard RNA protocols |